A Fuzzy Logic-Based Diagnostic Model for Lung Cancer Detection: An Improved Clinical Decision Support Framework

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Avikshit Sharma
Hamant Kumar

Abstract

Lung disease, and lung cancer above all, remains one of the toughest problems in global health, taking a heavy toll each year because diagnosis so often arrives late or turns out to be wrong. The real clinical difficulty is not detection in general but catching disease at an early stage, when treatment has the best chance of working. Standard diagnostic methods tend to falter when symptom data is vague or overlapping in nature, which is exactly the situation fuzzy logic is built to handle: it reasons under uncertainty while still giving clinicians an interpretable output. This paper reports a full study built around five linked goals. First, the relevant diagnostic parameters for selected lung diseases were gathered and consolidated from the clinical literature. Second, a new Mamdani-type fuzzy inference system was designed, with membership functions chosen specifically for the parameters identified. Third, established fuzzy diagnostic models from the literature were re-implemented and run against real patient data so their reported performance could be checked rather than simply cited. Fourth, the newly proposed model was tested under the same conditions. Fifth, all of the models were placed side by side in a structured comparison that looks beyond raw accuracy to include interpretability, execution time, confidence output, and treatment guidance. Testing on the benchmark UCI lung cancer dataset shows the proposed model reaching a mean accuracy of 97.10 percent under 10-fold cross-validation, without discarding any of the original features through dimensionality reduction, and producing confidence values that carry genuine clinical meaning. Taken together, the work delivers both a working diagnostic model and a comparison framework intended to steer future research in intelligent, fuzzy-logic-based healthcare decision support....

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How to Cite
Sharma, A., & Kumar, H. (2026). A Fuzzy Logic-Based Diagnostic Model for Lung Cancer Detection: An Improved Clinical Decision Support Framework . CINEFORUM, 66(S6), 617–624. Retrieved from https://revistadecineforum.com/index.php/cf/article/view/1653
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Original Articles

References

American Cancer Society, “Cancer Facts & Figures 2022,” Atlanta: American Cancer Society, 2022.

World Health Organization, “Cancer Key Facts,” https://www.who.int/news-room/fact-sheets/detail/cancer, accessed March 2023.

R. L. Siegel, K. D. Miller, N. S. Wagle, and A. Jemal, “Cancer statistics, 2023,” CA: A Cancer Journal for Clinicians, vol. 73, no. 1, pp. 17-48, 2023.

S. Bharati, P. Podder, and M. R. H. Mondal, “Hybrid deep learning for detecting lung diseases from X-ray images,” Informatics in Medicine Unlocked, vol. 20, p. 100391, 2020.

L. A. Zadeh, “Fuzzy sets,” Information and Control, vol. 8, no. 3, pp. 338-353, 1965.

E. H. Mamdani and S. Assilian, “An experiment in linguistic synthesis with a fuzzy logic controller,” International Journal of Man-Machine Studies, vol. 7, no. 1, pp. 1-13, 1975.

T. J. Ross, Fuzzy Logic with Engineering Applications, 3rd ed., Chichester: John Wiley & Sons, 2010.

K. Polat and S. Gunes, “Principles component analysis, fuzzy weighting pre-processing and artificial immune recognition system based diagnostic system for diagnosis of lung cancer,” Expert Systems with Applications, vol. 34, no. 1, pp. 214-221, 2008.

E. Avci, “A new expert system for diagnosis of lung cancer: GDA-LS-SVM,” Journal of Medical Systems, vol. 36, no. 3, pp. 2005-2009, 2011.

M. R. Daliri, “A hybrid automatic system for the diagnosis of lung cancer based on genetic algorithm and fuzzy extreme learning machines,” Journal of Medical Systems, vol. 36, no. 2, pp. 1001-1005, 2012.

A. Alharbi, “An automated computer system based on genetic algorithm and fuzzy systems for lung cancer diagnosis,” International Journal of Nonlinear Sciences and Numerical Simulation, 2018. DOI: 10.1515/ijnsns-2017-0048.

U. Ahmed, G. Rasool, H. F. Maqbool, and S. Zafar, “Fuzzy rule based diagnostic system to detect the lung cancer,” in Proc. IEEE Conf., 2018, pp. 1-6.

A. Onan, “A fuzzy-rough nearest neighbor classifier combined with consistency-based subset evaluation and instance selection for automated diagnosis of breast cancer,” Expert Systems with Applications, vol. 42, no. 20, pp. 6844-6852, 2015.

A. Alharbi and F. Tchier, “Using a genetic-fuzzy algorithm as a computer aided diagnosis tool on Saudi Arabian breast cancer database,” Mathematical Biosciences, vol. 286, pp. 39-48, April 2017.

M. F. Ganji and M. S. Abadeh, “A fuzzy classification system based on ant colony optimization for diabetes disease diagnosis,” Expert Systems with Applications, vol. 38, no. 12, pp. 14650-14659, 2011.

H. L. Chen, C. C. Huang, X. G. Yu, X. Xu, X. Sun, and G. Wang, “An efficient diagnosis system for detection of Parkinson's disease using fuzzy K-nearest neighbor approach,” Expert Systems with Applications, vol. 40, no. 1, pp. 263-271, 2013.

D. Y. Liu, H. L. Chen, B. Yang, L. N. Li, and J. Liu, “Design of an enhanced fuzzy K-nearest neighbor classifier based on computer aided diagnostic system for thyroid disease,” Journal of Medical Systems, vol. 36, no. 5, pp. 3243-3254, 2012.

M. S. Durai and N. C. S. Iyengar, “Effective analysis and diagnosis of lung cancer using fuzzy rules,” International Journal of Engineering Science and Technology, vol. 2, no. 6, pp. 2102-2108, 2010.

N. H. Phuong, H. C. Le Huu Nghia, and Y. S. Kwak, “LDDS - A fuzzy rule based lung diseases diagnostic system combining positive and negative knowledge,” in Proc. Int. Conf. on Fuzzy Systems and Knowledge Discovery, 2003.

S. S. Hecht, “Tobacco smoke carcinogens and lung cancer,” JNCI: Journal of the National Cancer Institute, vol. 91, no. 14, pp. 1194-1210, 1999.

S. Markowitz, A. Morabia, and A. Miller, “Asbestos, asbestosis, smoking, and lung cancer: study bias and confounding issues,” American Journal of Respiratory and Critical Care Medicine, vol. 189, pp. 116-117, 2014.

National Comprehensive Cancer Network, “NCCN Clinical Practice Guidelines in Oncology: Non-Small Cell Lung Cancer, Version 3.2023,” https://www.nccn.org, 2023.

C. J. Merz and P. M. Murphy, “UCI Machine Learning Repository,” University of California, School of Information and Computer Science, Irvine, CA, 2010. http://archive.ics.uci.edu/ml

G. Litjens, T. Kooi, B. E. Bejnordi et al., “A survey on deep learning in medical image analysis,” Medical Image Analysis, vol. 42, pp. 60-88, 2017.

F. Feng, Y. Wu, Y. Wu, G. Nie, and R. Ni, “The effect of artificial neural network model combined with six tumor markers in auxiliary diagnosis of lung cancer,” Journal of Medical Systems, vol. 36, no. 5, pp. 2973-2980, 2012.

M. R. Daliri, “Feature selection using binary particle swarm optimization and support vector machines for medical diagnosis,” Biomedical Engineering / Biomedizinische Technik, vol. 57, no. 5, pp. 395-402, 2014.

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